Umme Urmi
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel strain of coronavirus that has not been previously identified in humans. On 11 March 2020, the World Health Organization (WHO) declared SARS-CoV-2 as a pandemic that causes novel coronavirus disease 2019 (COVID-19). Transmission among humans occurs via close contact with an infected individual that produces respiratory droplets while coughing or sneezing within a range of about 6 feet. The viruses can be deposited on the surface by aerosols generated while talking, coughing or sneezing. Disinfection of surfaces is an important strategy in containing the transmission of this virus. Therefore, antimicrobial coatings that can kill the viruses will help in preventing transmission and spread of these viruses. This project will evaluate the efficacy of novel antimicrobial peptide mimics developed and patented in-house against coronaviruses and develop antimicrobial surface coatings to prevent the spread of the virus. There has been a significant increase in the use of disinfectant since the onset of the COVID-19 pandemic. However, repeated, and long-term use of disinfectants can result in accumulation of chemical residue affecting human health and environment. This research will also examine the synergy of the novel antimicrobial peptides with currently used common disinfectants. Antimicrobial synergy is the phenomenon where two antimicrobials exhibit enhanced activity that is greater than the sum of their individual activity. This will allow for development of disinfectants that are effective against coronaviruses at much lower concentrations and non-toxic to humans and the environment.
Biography
Urmi completed her MS in Microbiology from Jahangirnagar University, Bangladesh in 2018. Her research was focused on antimicrobial resistance (AMR). For next three years she worked for One Health Laboratory, Jahangirnagar University; RT-PCR laboratory under UNFPA project, and WorldFish to lead AMR/One health project. She received university international postgraduate awards (UIPA) in 2021 and started her interdisciplinary PhD journey under the supervision of Dr. Ajay Kumar Vijay, Professor Mark Willcox and Dr. Salequl Islam. Urmi鈥檚 study focuses on the different types of antimicrobial peptide, their synergistic relationship, and efficacy against novel coronavirus.
Education
PhD at University of New South Wales, Sydney (current)
Master of Science in Microbiology at Jahangirnagar University, Bangladesh (2018)
Bachelor of Science in Microbiology, Jagangirnagar University, Bangladesh (2016)聽
- Publications
- Awards
- Grants
- Media
- Affiliations and Memberships
Publications
Journal Articles
- Bayasrin Ara, Umme Laila Urmi, Tanjum Ara Haque, Shamsun Nahar,Adity Rumnaz, Tamanna Ali, Mohammed Shah Alam, Abu Syed Md. Mosaddek, Nor Azlina A Rahman, Mainul Haque, and Salequl Islam. 鈥淢obile Colistin-Resistance Gene variants (mcr-1 and mcr-2) Detected in Urinary Tract Pathogens in Bangladesh: The Last Resort of Infectious Disease Management Colistin Efficacy is Under Risk鈥. Expert rev of Clinical Pharmacology Journal, 2021.
- Tamman Ali, Adity Rumnaz, Umme Laila Urmi, Shamsun Nahar, Masud Rana, Fahmida Sultana, Samiul Iqbal, Md. Muklesur Rahman, Nor Azlina A Rahman, Salequl Islam, Mainul Haque. 鈥淭ype-2 Diabetes Mellitus (T2DM) Individuals Carry Different Periodontal Bacteria鈥. Pesquisa Brasileira em Odontopediatria e Cl铆nica Integrada, 2021. Cl铆nica Integrada 2021. doi.org/10.1590/pboci.2021.049
- Salequl Islam, Umme Laila Urmi, Masud Rana, Fahmida Sultana, Nusrat Jahan, Billal Hossain, Samiul Iqbal, Md. Moyazzem Hossain, Abu Syed Md. Mosaddek and Shamsun Nahar. 鈥淗igh Abundance of Colistin Resistant mcr-1 Gene in Poultry Chicken Gut-Bacteria in Bangladesh鈥. Scientific Reports, 2020. doi:
- Umme Laila Urmi, Shamsun Nahar, Masud Rana, Fahmida Sultana, Nusrat Jahan, Billal Hossain, Mohammed Shah Alam, Abu Syed Md. Mosaddek, Judy McKimm, Nor Azlina A Rahman, Salequl Islam, Mainul Haque. 鈥淕enotypic to Phenotypic Resistance Discrepancies Identified involving 尾-lactamase genes, blaKPC, blaIMP, blaNDM-1, and blaVIM in uropathogenic Klebsiella pneumoniae鈥. Infection and Drug Resistance, 2020. doi: 10.2147/IDR.S262493
- Salequl Islam, Mohammad Ali Moni, Umme Laila Urmi, Atsushi Tanaka, and Hiroo Hoshino 鈥淐-C chemokine receptor-like 2 (CCRL2) Acts as Coreceptor for Human Immunodeficiency Virus-2鈥. Briefings in Bioinformatics, 2020. doi: 10.1093/bib/bbaa333
- Umme Laila Urmi, Nusrat Jahan, Shamsun Nahar, Masud Rana, Fahmida Sultana, Billal Hossain, Samiul Iqbal, Moyazzem Hossain, Abu Syed Md Mosaddek, and Salequl Islam. 鈥淕ram positive uropathogens: Empirical treatment and emerging antimicrobial resistance鈥. Biomedical Research and Clinical Practice, April 2019.doi: 10.15761/BRCP.1000182
Conference Abstracts
- M. Islam, M. Al Asad, S. Sarker, R. Muhit, N. Islam, A. Siddique Shanta, U. Laila Urmi, S. Nahar. 鈥淐ulture-independent Real-time Pcr Detected A Plethora Of Colistin Resistance Genes (mcr1-mcr5) In Chicken- And Fish-gut Contents In Bangladesh鈥. American Society of Microbiology (ASM) Microbe, 2021, USA.
- M.U.L. Urmi, S. Sultana, F. Akter, B. Ara, T.A. Haque, A.S. Md. Mosaddek, D.S. Nahar, D.S. Islam. 鈥淢odifications of mgrB instigate colistin resistance in poultry gut-isolates in Bangladesh鈥. International Journal of Infectious Disease (ICID), December, 2020.
- Salequl Islam, Umme Laila Urmi, Masud Rana, Fahmida Sultana, Nusrat Jahan, Billal Hossain, Samiul Iqbal, Abu Syed Md. Mosaddek and Shamsun Nahar. 鈥淧oultry chicken gut-bacteria carry high extent of colistin resistant mcr-1 gene in Bangladesh鈥. International Journal of Infectious Disease (ICID), December, 2020.
- T.A. Haque, B. Ara, M.U.L. Urmi, S. Sultana, F. Akter, A.S. Md. Mosaddek, S. Nahar, D.S. Islam.鈥淧lasmid mediated genes and mutation in gyrA gene confer quinolone 鈥 Antibiotic resistance in Enterobacteriaceae independently鈥. International Journal of Infectious Disease (ICID), December, 2020.
- Salequl Islam , Umme Laila Urmi , Tanjum Ara Haque , Bayasrin Ara, Fahima Khatun, Abu Syed Md. Mosaddek , Rinat Rizvi , M Shahabuddin Kabir Choudhuri , and Shamsun Nahar. "The First Human Report of Mobile Colistin-Resistant Gene, mcr-1 in Urinary and Diarrheal Pathogens in Bangladesh" American Society of Microbiology (ASM) Microbe, 2020.
- Shamsun Nahar, Umme Laila Urmi, Subrina Sultana , Fatama Akter, Bayasrin Ara , Tanjum Ara Haque,Abu Syed Md. Mosaddek and Salequl Islam 鈥淧leiotropic Resistance Role of New Delhi Metallo-尾-Lactamase-1 (blaNDM-1) Gene Against Aminoglycoside Antibiotics in Uropathogen Bacteria鈥. American Society for Microbiology (ASM) Microbes, January 28鈥30, 2020 in Arlington, Virginia, USA.
- Tanjum Ara Haque, Bayasrin Ara, Adity Rumnaz, Tamanna Ali, Umme Laila Urmi, Mohammed Shah Alam, Subrina Sultana, Fatama Akter, Abu Syed Md.Mosaddek, Shamsun Naha, and Salequl Islam. 鈥淎ssociation of Phenotypic Quinolone Resistance in Enterobacteriaceae to their Plasmid Mediated Genes鈥. 33rd conference, Bangladesh Society of Microbiologists (BSM), 26th December, 2019, Bangladesh.
- Salequl Islam, Umme Laila Urmi, Masud Rana, Nusrat Jahan, Fahmida Sultana, Billal Hossain, Samiul Iqbal, and Shamsun Nahar. 鈥淧rophylactic Uses of Antimicrobials in Bangladeshi Poultry Drive Microbial Resistance鈥. American Society for Microbiology (ASM) Biothreat. Feb 12-14, 2018. Baltimore, MD, USA.
- Shamsun Nahar, Fahmida Sultana, Masud Rana, Nusrat Jahan, Billal Hossain, Samiul Iqbal, Azizur Rahman, Umme Laila Urmi, and Salequl Islam. 鈥淧rior Exposures of Antimicrobial Contribute Acquisition of Mobile Colistin Resistance (mcr-1) Gene into Bangladeshi Poultry Microbiota鈥. American Society for Microbiology (ASM) Microbes, 2018, Atlanta, USA.